Plasma calcitonin gene‐related peptide (CGRP) in migraine and endometriosis during the menstrual cycle
نویسندگان
چکیده
منابع مشابه
Calcitonin gene related peptide (CGRP)-provoked migraine-like attacks.
In this issue of Cephalalgia, Dr Jakob Moller Hansen and his colleagues report a series of very interesting experiments in which they successfully induced migraine-like attacks in patients with migraine with aura via infusion of calcitonin gene related peptide (CGRP). This work echoes similar experiments carried out by the Copenhagen group using the nitric oxide donor, glycerol trinitrate (GTN)...
متن کاملCalcitonin Gene-Related Peptide (CGRP)
Calcitonin gene-related peptide (CGRP) is a 37 amino acid vasoactive neuropeptide that is widely distributed in central and peripheral nervous systems in mammals. CGRP was discovered in 1982 by molecular cloning of calcitonin (CT) gene. CGRP-specific mRNA appears to predominate in the hypothalamus while CT mRNA predominates in the thyroid. CGRP has an amphiphilic α-helical secondary structure i...
متن کاملThe Relationship between Plasma Antioxidant Enzymes Activity and Sex Hormones during the Menstrual Cycle
Abstract Background and objective: There is increasing evidence for the role of oxidative stress in female reproductive tract. The purpose of this study was to determine the activity of antioxidant enzymes during menstrual cycle. In addition, the relationship between activity of antioxidant enzyme and sex hormones was evaluated. Materials and methods: In this study the activity of superoxi...
متن کاملEndogenous pain inhibition during menstrual cycle in migraine.
BACKGROUND Migraine is a common headache disorder that can vary menstrually in women and has been linked to an impairment of endogenous pain inhibitory systems. One of these endogenous pain inhibitory systems, namely conditioned pain modulation (CPM; formerly diffuse noxious inhibitory controls-like), has been shown to be affected by the menstrual cycle. The aim of this study was to examine CPM...
متن کاملSerotonin concentrations in plasma and variations during the menstrual cycle.
We used a specific and sensitive radioenzymatic method to establish a reference interval for the concentration of serotonin in platelet-poor plasma in 98 healthy volunteers (49 men, 49 women). The interval was 0-11 nmol/L with a median of 2.8 nmol/L. No difference in concentration in relation to sex or age was observed. In a group of eight very old volunteers (ages 86-92 years), however, concen...
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ژورنال
عنوان ژورنال: Annals of Clinical and Translational Neurology
سال: 2021
ISSN: 2328-9503,2328-9503
DOI: 10.1002/acn3.51360